Postdoctoral Fellow – Pediatric Intestinal Failure Research

About the role

Saint Louis University seeks a motivated postdoctoral fellow to join a multidisciplinary team investigating pediatric intestinal failure, short bowel syndrome, and related systemic diseases. The fellow will work across neonatal large‑animal models, organoid cultures, and human tissue studies to uncover mechanisms of intestinal adaptation, barrier function, and liver‑gut communication.

Key responsibilities

• Design, execute, and analyze experiments using large‑animal models, epithelial and liver organoid systems, and molecular assays.
• Perform sample collection, processing, and functional assays such as immunostaining, imaging, qPCR, ELISA, microbiome and metabolomic analyses.
• Integrate physiological, histological, molecular, and multi‑omic datasets to generate comprehensive insights.
• Maintain detailed laboratory records, develop protocols, and ensure quality control.
• Prepare figures, manuscripts, and present findings at lab meetings and scientific conferences.

Required profile

• PhD, MD, MD/PhD, DVM, or equivalent in biology, physiology, molecular biology, immunology, pathology, nutrition, or related fields.
• Experience with cell culture, organoid systems, molecular biology techniques, and animal models, preferably large‑animal models.
• Strong written and oral communication skills and ability to work both independently and collaboratively.

Required skills

• Cell culture and organoid techniques
• Molecular biology (qPCR, ELISA, multiplex assays)
• Animal model handling, especially neonatal large‑animal models
• Microbiome and metabolomics sample preparation and analysis
• Histology and immunostaining
• Bioinformatics and multi‑omic data integration