Associate Director, Quantitative Pharmacology & Pharmacometrics (Immuno‑Oncology)

About the role

We are looking for an experienced scientist to lead quantitative pharmacology and pharmacometrics activities for immuno‑oncology programs within our Global Clinical Development organization. The Associate Director will act as the subject‑matter expert, shaping model‑based strategies and supporting decision‑making from early development through registration.

Key responsibilities

• Represent QP2‑IO on oncology clinical development teams and define critical model‑based questions.
• Develop and execute translational PK/PD, population PK, exposure‑response, clinical trial simulation, disease progression and QSP models.
• Model tumor‑size and survival endpoints, including proportional‑hazards analyses.
• Author regulatory documents (INDs, CSRs, CTDs) and present QP2‑IO data at regulatory meetings.
• Collaborate with cross‑functional scientists, external vendors and partners to align quantitative frameworks.

Required profile

• Ph.D. in a relevant scientific discipline with ≥3 years of pharmacometrics experience, or PharmD/MS with 5‑7 years of relevant experience.
• Demonstrated impact using pharmacometrics methods in drug development.
• Professional written and verbal communication skills.

Required skills

• Proficiency in R and NONMEM (or equivalent modeling languages).
• Experience with Phoenix WinNonlin, PK/PD modeling, population pharmacokinetics, and quantitative systems pharmacology.
• Ability to design experiments, perform statistical analysis and interpret complex data.

What we offer

• Base salary $156,900 – $247,000 per year, plus annual bonus and long‑term incentives.
• Comprehensive health, dental, vision, 401(k) and paid time‑off benefits.
• Hybrid work arrangement with flexibility for remote work when not within commuting distance.