Senior Scientist - PKDM-BA (Immunoassay)

About the role

Amgen is seeking a Senior Scientist for Non-Regulated Immunoassays to join its PKDM organization at its Thousand Oaks, California site. The role supports biologics programs by developing, qualifying, validating and running non-regulated immunoassays used for pharmacokinetic and soluble target protein measurements. It is highly laboratory focused and requires strong hands-on expertise and a track record of building and running assays across multiple platforms.

Key responsibilities

• Develop, optimize, qualify, validate and run non-regulated immunoassays for pharmacokinetic and soluble target protein measurements
• Analyze samples using ELISA, MSD/ECL, Gyrolab, Quanterix, AlphaLISA and other platforms
• Design experiments, troubleshoot issues, interpret results and improve assays
• Perform assay transfer, method qualification and validation
• Report findings in technical reports, presentations and team discussions
• Collaborate with scientists in Discovery Research, Precision Medicine, Translational Safety and Risk Sciences and other areas
• Maintain lab records and data management practices
• Support instrument maintenance, reagent qualification, inventory management and process improvements

Required profile

• PhD, PharmD or MD (with relevant post-doc), or Master's degree with 3 years of scientific experience, or Bachelor's degree with 5 years of scientific experience
• Preferred: Master's in Immunology, Biochemistry, Bioanalytical Sciences, Pharmaceutical Sciences or related field
• Preferred: 3-5 years of industry or CRO experience in immunoassay development and bioanalysis
• Preferred: experience with pharmacokinetic and soluble target protein measurements for biologics

Required skills

• Hands-on immunoassay platforms such as ELISA, MSD/ECL, Gyrolab, Quanterix, AlphaLISA
• Assay optimization, bioanalytical best practices and data interpretation
• Technical report writing and presentation of scientific results
• Cross-functional teamwork and attention to detail

What we offer

• Annual salary range of $130,384 to $176,401, varying with skills and experience
• Health, dental and vision coverage, life and disability insurance, and a retirement savings plan with company contributions
• Discretionary annual bonus or sales-based incentive plan, stock-based long-term incentives
• Award-winning time-off plans and flexible work models where possible