Associate Director, Quantitative Pharmacology & Pharmacometrics – Immunology
msd
Job description
About the role
The Associate Director will lead mechanistic modeling efforts to support translational and drug development research in immunology, collaborating across functional teams and external partners.
Key responsibilities
- Design and execute model analysis plans using PK/PD, PBPK, QSP, and other mechanistic approaches.
- Integrate preclinical and clinical data to inform dose selection, trial design, and go/no‑go decisions.
- Perform clinical trial simulations, comparator modeling, and model‑based analyses.
- Mentor team members and share modeling expertise to advance departmental science.
Required profile
- Ph.D. (or PharmD, MS) with 4–8 years of relevant experience in pharmaceutical drug development, regulatory agencies, or academia.
- Strong background in biopharmaceutics, pharmacometrics, mathematics, statistics, computational biology, or related engineering fields.
- Demonstrated ability to work independently and influence cross‑functional teams.
Required skills
- Hands‑on population PK/PD and QSP modeling using Phoenix, R, Matlab, NONMEM, Monolix.
- Advanced experimental design, mathematical problem solving, and data interpretation.
- Proficiency in written and verbal communication and interdisciplinary collaboration.
What we offer
- Salary range $156,900 – $247,000 per year, with annual bonus and long‑term incentives.
- Comprehensive benefits including medical, dental, vision, 401(k), paid holidays, vacation, and sick days.
- Hybrid work arrangement and domestic relocation support.
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Published 6 hours ago
Expires 1 month from now
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