Senior Scientist, Integrated Computational and Experimental Inflammation Discovery

About the role

Amgen is hiring a Senior Scientist to lead scientific activities in its Inflammation discovery programs. The role advances discovery by combining rigorous bench experiments with computational evidence, working independently and under minimal direction to inform therapeutic hypotheses and target programs.

Key responsibilities

• Independently design, run, analyze and interpret wet-lab experiments that test therapeutic hypotheses and support target identification, validation and progression.
• Use experimental, computational, AI-enabled and data-analytic approaches to build mechanistic insight and integrate findings across data sources.
• Develop decision criteria and give evidence-based recommendations for target and program go/no-go decisions.
• Lead work groups and project teams, coordinating contributions from multiple disciplines.
• Develop and implement novel scientific approaches, technologies and workflows that improve efficiency and translational relevance.
• Build expertise in small- and large-molecule drug discovery and coach colleagues on scientific and technical matters.
• Communicate project data and recommendations internally and externally, and contribute to publications, presentations, patents and technical reports.

Required profile

• PhD, PharmD or MD (with relevant post-doc), or Master's degree with 3 years of relevant scientific experience, or Bachelor's degree with 5 years of relevant scientific experience.
• Ability to work independently, make independent scientific decisions and lead scientific activities in project teams.
• Strong written and verbal communication, and experience sharing scientific advice with colleagues.

Required skills

• Experience designing and running experimental studies for target discovery, validation or hypothesis testing.
• Experience with computational biology, AI-enabled tools, advanced data analytics, multimodal data integration or predictive modeling.
• Contributions to scientific documents such as posters, presentations, publications, regulatory documents, patent applications and technical reports.
• Basic knowledge of adjacent fields such as translational science, human genetics, clinical biology, computational biology, protein engineering or small-molecule discovery.

What we offer

• A competitive annual salary range (posted for the U.S., excluding Puerto Rico).
• Health, dental and vision coverage, life and disability insurance, and a retirement savings plan with company contributions.
• Discretionary annual bonus or sales-based incentive plan, stock-based long-term incentives, and flexible work models where possible.