Research Scientist – Bioanalytics/SPR

About the role

The Biologics Research Center (BRC) at Novartis discovers and develops biologic therapeutics for oncology, autoimmune, respiratory and cardiovascular diseases. Its Bioanalytics group characterizes and identifies lead molecules as biotherapeutic candidates, evaluating recombinant protein and cell binding, epitope binning and functional activity. This Research Scientist IIPosition is onsite in Cambridge, MA, and requires direct experience in antibody characterization by surface plasmon resonance (e.g., Biacore).

Key responsibilities

• Become proficient in developing Biacore methods to meet project objectives, then independently analyze and interpret Biacore data, draw conclusions, generate hypotheses and run follow-up experiments with input from senior lab members.
• Learn mammalian cell culture and cellular binding technologies (e.g., Kinexa, LigandTracer) to characterize antibodies binding to cells.
• Provide basic data analysis across learned assays, assessing whether each experiment's hypothesis was properly tested.
• Work in interdisciplinary teams, collaborating with others and training junior associates as needed.
• Present research findings in slide decks and take part in project teams and lab meetings.

Required profile

• MS or equivalent in biology, chemistry, pharmacology or a related field with less than 2 years of experience; or a BS/apprenticeship with more than 2 years of relevant experience in drug discovery or laboratory research (not a PhD-level position).
• Direct experience in antibody characterization by surface plasmon resonance (e.g., Biacore).
• Strong interpersonal skills and demonstrated Novartis values: team spirit, scientific drive, flexibility, organization and communication.

Required skills

• Surface plasmon resonance (Biacore)
• Desirable: binding characterization with other approaches (Fortebio, Kinexa, flow cytometry, LigandTracer) and functional assays (ELISA)
• Desirable: mammalian cell culture

What we offer

• Expected salary of $81,200 to $150,800 per year, with a performance-based cash incentive and possible annual equity awards.
• US-based eligible employees receive health, life and disability benefits, a 401(k) with company contribution and match, and a time-off package including vacation, personal days and holidays.