Senior Scientist, Large Molecule Bioanalytical - Data Science

About the role

IQVIA Laboratories in Indiana is seeking a Senior Scientist, Large Molecule Bioanalytical to organize, curate and scientifically evaluate LC/MS data from early drug discovery ADME studies. The role ensures that complex datasets are accurate, consistent and traceable, turning them into actionable insights that support compound profiling, lead optimization and data-driven program decisions.

Key responsibilities

• Manage and curate LC/MS datasets from non-regulatory ADME bioanalysis studies supporting exploratory and pilot toxicology in vivo PK/PD studies
• Ensure accuracy, completeness, consistency and traceability of data from raw LC/MS outputs through processed results and internal reports
• Perform scientific quality-control reviews to identify outliers, errors and analytical or method-related artifacts
• Evaluate ADME parameters across compounds, projects and assay formats to support structure-activity and structure-property relationships
• Collaborate with DMPK, analytical, informatics and project teams to improve pipelines, automation, visualization tools and analytical efficiency
• Coordinate internal and external CRO data contributions while keeping study designs, metadata, analytical methods and outputs aligned
• Prepare summaries, tables, figures, dashboards and integrated discovery data packages for compound progression and portfolio decisions
• Establish standardized data formats, naming conventions, metadata practices and reproducible workflows

Required profile

• Bachelor's or master's degree in analytical chemistry, pharmacokinetics, pharmaceutical sciences, biochemistry or a related field; equivalent education, training and experience may be accepted
• 3-7+ years of experience with LC/MS data in discovery-stage ADME or DMPK settings
• Strong understanding of LC/MS workflows, quantitative data analysis and common discovery ADME assays
• Experience evaluating data quality and identifying analytical, method-related and data-processing artifacts
• Familiarity with high-resolution mass spectrometry bioanalytical data for large molecules, new modalities or biomarkers

Required skills

• Analytical thinking and ability to turn complex datasets into clear insights
• Scientific rigor, attention to detail and a strong data-integrity mindset
• Cross-functional collaboration with bioanalytical scientists, DMPK teams, CROs, informatics teams and IT partners
• Clear communication of data assumptions, limitations, trends and conclusions to scientific stakeholders
• Knowledge of bioanalytical workflows for modalities such as oligonucleotides, proteins, peptides, antibody-drug conjugates, ionizable lipids and amino acids

The potential base pay range is $64,200 to $133,600 per year, depending on qualifications, location and schedule; additional compensation may include incentives, bonuses and benefits.