Senior Research Technician – Antibiotic Discovery Center

About the role

The Antibiotic Discovery Center at Northeastern University seeks a motivated Senior Research Technician to develop and operate a target‑based screening platform for antibiotic discovery, support hit validation, and maintain laboratory operations in a collaborative research environment.

Key responsibilities

• Develop and execute a microfluidics‑based high‑throughput screening platform.
• Perform biochemical and microbiological assays for antibacterial target identification and validation.
• Support assay development, optimization, data analysis, and high‑throughput screening campaigns.
• Participate in hit triage, secondary assays, natural product isolation, and structure‑activity studies.
• Operate and maintain screening and purification equipment (LC, HPLC, plate readers, microfluidics sorters).
• Manage lab inventories, safety compliance, and instrument calibration.
• Prepare reports, presentations, and provide training to students and new lab members.

Required profile

• Bachelor’s or Master’s degree in Microbiology, Biochemistry, Chemistry, Molecular Biology, or related field.
• 2–3 years of hands‑on research experience in academic or industrial settings.
• Strong organizational and communication abilities in a dynamic research environment.

Required skills

• Molecular cloning
• Bacterial culture
• Biochemical or enzymatic assays
• Natural product extraction
• Chromatographic purification (LC, HPLC)
• Analytical instrumentation (LC‑MS)
• Microfluidics equipment operation

What we offer

• Comprehensive benefits package including medical, vision, dental, and paid time off.
• Tuition assistance, wellness & life programs, retirement plans.
• Commuting and transportation benefits.