Senior Manager, Global Patient Safety Business Excellence

About the role

Amgen is looking for a Senior Manager to lead business excellence initiatives across Global Patient Safety (GPS). The role provides leadership in project management, organizational change management, governance, compliance oversight and operational effectiveness, partnering with GPS and cross-functional stakeholders to deliver business-critical initiatives, strengthen inspection readiness and advance a culture of continuous improvement.

Key responsibilities

• Lead the development, implementation and continuous improvement of project management and change management standards, methodologies and best practices across GPS.
• Drive and sustain GPS governance frameworks, ensuring effective oversight, decision-making and alignment with organizational objectives.
• Deliver business-critical initiatives within GPS and represent GPS on enterprise-wide cross-functional programs.
• Provide strategic leadership and oversight for pharmacovigilance activities related to mergers, acquisitions, licensing agreements and divestitures.
• Contribute to the GPS Quality Management System and ensure compliance with global regulatory requirements.
• Support Health Authority inspections, business partner audits and internal process audits, including logistics and operational support.
• Develop, monitor and report key performance and compliance metrics, and facilitate cross-functional management of deviations, CAPAs and quality improvement initiatives.
• Build partnerships with internal and external stakeholders and champion digital transformation through automation, analytics and emerging technologies.

Required profile

• Basic: doctorate with 2 years of safety project management experience, or master's with 4 years, or bachelor's with 6 years, or associate's with 10 years, or high school diploma with 12 years of safety project management experience.
• Preferred: proven expertise in project management, change management and organizational transformation; ability to interpret pharmacovigilance regulations and compliance requirements; experience working internationally and with cross-functional teams; critical thinking and decision-making skills; ability to manage multiple priorities and time constraints.
• Preferred: PMP certification or equivalent in change or project management; experience executing major projects in regulatory or safety environments, including M&A and divestitures in life sciences; experience with fully remote teams across time zones; experience presenting to and influencing senior leadership; experience establishing governance frameworks and leading enterprise-wide initiatives; experience in pharmacovigilance, drug safety, regulatory affairs, quality or related life sciences functions; experience with Lean, Six Sigma, Agile or similar process improvement methods.

What we offer

• Annual salary range posted for the U.S. (excluding Puerto Rico), varying with skills, experience and qualifications.
• Total rewards including health, dental and vision coverage, life and disability insurance, flexible spending accounts, retirement savings plan with company contributions, and a discretionary annual bonus or sales-based incentive plan.
• Stock-based long-term incentives, time-off plans and flexible work models where possible.