Scientist 3, Immunology

About the role

The Department of Immunology at Genentech is looking for a Scientist 3 to investigate novel biological mechanisms and potential therapeutic targets for inflammatory diseases. The role leads projects that advance understanding of adaptive and innate immunity, with a focus on using immunoregulatory mechanisms to restore immune and tissue homeostasis during inflammation. The candidate works independently and collaboratively on pipeline projects, moving research-stage programs toward early clinical development.

Key responsibilities

• Lead projects advancing research-stage programs into early clinical development, providing scientific and technical expertise and generating proof of concept data.
• Develop in vitro and in vivo skills to test novel pathways and molecules in inflammatory disease pathogenesis and to define the mechanism of action of new targets.
• Collaborate with other labs in immunology, regenerative medicine, human genetics, biomarker discovery and early clinical development.
• Present research at intra- and inter-departmental meetings.

Required profile

• PhD in immunology, molecular biology, biochemistry or a related field with a record of high-quality publications.
• Prior industry experience, particularly in target discovery.
• Extensive hands-on experience in cellular and molecular immunology techniques, including primary cell isolation, in vitro immunological assays, multi-dimensional flow cytometry and in vivo animal models.
• Ability to design, run and interpret experiments independently, and excellent communication skills.

Preferred

• Strong background in adaptive and innate immunity.
• Experience with precision genome editing for cell engineering.
• Analysis of genomic sequencing, scRNA-seq, TCR-seq, CITE-seq or spatial transcriptomics data.
• In vivo immunological techniques and industry target discovery experience.

What we offer

• Salary range of $103,400 to $192,000 for California-based candidates; actual pay depends on experience, qualifications and location.
• A discretionary annual bonus may be available.
• Relocation benefits are available for this posting.