Scientist 3, Animal Genetic Technologies (Warming Lab)

About the role

Genentech is looking for a Scientist 3 to join its Animal Genetic Technologies department in a South San Francisco lab that develops and uses state-of-the-art technology for in vivo genome manipulation. The Warming lab works closely with the animal model generation group and colleagues across therapeutic areas and the Genentech research community.

Key responsibilities

• Develop and use genome editing technology, including CRISPR, together with classic mouse genetics approaches
• Identify novel modifiers of disease and validate new targets for therapeutic intervention
• Create and genetically analyse animal models to support target discovery and validation

Required profile

• Ph.D. degree, or equivalent, in genetics and/or molecular biology, with relevant postdoctoral experience
• 3+ years of post-PhD or biotechnology/pharmaceutical industry experience
• Hands-on experience with the mouse as a model system, with a published track record
• Solid molecular biology skills and a strong publication record in fields such as model organism genetics, stem cells, genome editing and/or synthetic biology
• Exceptional organisational and communication skills, able to work independently and cooperatively in a fast-paced team
• Strong interest in technology development and exploring the molecular basis of disease using in vivo models and genome editing technologies

Required skills

• CRISPR and NGS-based technologies (RNA-seq, ChIP-seq, scRNA-seq, long-read sequencing)
• Microscopy, flow cytometry and imaging
• Preferred: basic hands-on experience with bioinformatics workflows and computational sequence analysis pipelines
• Preferred: hands-on proficiency with viral vector platforms, especially AAV and lentiviral technologies

What we offer

• Expected salary range of $103,400 to $192,000, depending on experience, qualifications and location
• A discretionary annual bonus may be available
• Relocation benefits are available