Scientist 2, Translational CVRM

About the role

The Cardiovascular, Renal and Metabolism (CVRM) Translational Biology group within Genentech Research and Early Development is looking for a Scientist 2 to advance drug discovery by running in vivo experiments in rodent models of cardiometabolic diseases. The work is done in close collaboration with scientists in a multidisciplinary team in a fast-paced environment.

Key responsibilities

• Establish and run experiments in relevant rodent models and optimise approaches to model disease processes resembling human diseases
• Generate high-quality experimental data on strict timelines and project goals
• Communicate key findings at project meetings and recommend follow-up studies and prioritisation
• Apply relevant scientific knowledge to solve project problems and stay familiar with the scientific literature
• Work collaboratively in multidisciplinary project teams
• Analyse and document complex data with a focus on reproducibility, keeping accurate electronic lab notebook records

Required profile

• Bachelor's degree in pharmacology, biology or a related field with 6+ years of laboratory experience, or a Master's degree with 4+ years of experience in industry or academia
• Hands-on experience with cardiovascular models (myocardial infarction/ischaemia-reperfusion, transverse aortic constriction) and their phenotyping (echocardiography, heart catheterisation)
• Proficient survival surgery in rodents
• Experience with rodent handling, IV, IP, IM and SC drug administration, and non-terminal and terminal blood sampling and tissue harvest
• Preferred: experience with other cardiometabolic disease models

Required skills

• Detailed, analytical and organisational skills
• Strong communication skills
• Ability to work independently or in a team in a fast-paced setting
• Willingness to learn new skills and adapt to changing priorities

What we offer

• Salary range of $85,500 to $158,700 for the South San Francisco location, depending on experience and qualifications
• A possible discretionary annual bonus
• Relocation benefits are available