Process Development Senior Associate (Drug Substance Synthetics)

About the role

Amgen's Drug Substance Technologies - Synthetics (DSTS) group in Process Development is responsible for inventing, developing and implementing drug substance manufacturing processes and technologies for its synthetic and hybrid assets. It is looking for a Process Development Senior Associate in Thousand Oaks, California, who will work with chemists, process engineers and attribute scientists to support drug substance development and manufacturing from early to late stage. The role suits someone with prior lab-based research experience in bioconjugation.

Key responsibilities

• Work in a drug substance team to solve technical problems and contribute to safe, robust and cost-effective processes for synthetic and hybrid drug substances.
• Support cGMP manufacturing and technology transfer to internal facilities and external contract manufacturers.
• Support process characterization, including process understanding and modeling.
• Provide experimental results, technical updates, documentation, data interpretation and recommendations to drug substance teams.
• Work with a supervisor to advance projects within deadlines and cross-functionally to deliver regulatory documents and support regulatory filings.
• Follow good laboratory documentation practices and standard operating procedures.

Required profile

• Basic qualification: Master's degree, or Bachelor's degree with 2 years of scientific experience, or Associate's degree with 4 years, or high school diploma/GED with 6 years of scientific experience.
• Preferred: M.S. in organic chemistry or biochemistry/chemical biology with a specialization in bioconjugation chemistry, and prior bioconjugation experience in the biopharmaceutical or pharmaceutical industry.
• Demonstrated ability to work in a chemistry laboratory with minimal supervision, and to independently collect and interpret analytical results (NMR, HPLC, MS, IR, Raman, etc.).
• Excellent written and verbal communication, multitasking and project planning skills; a research summary with the CV is strongly encouraged.

What we offer

• Expected annual salary range of $80,044.50 to $108,295.50, depending on skills, experience and qualifications.
• Health, dental and vision coverage, life and disability insurance, and a retirement and savings plan with company contributions.
• Discretionary annual bonus or sales-based incentive plan, stock-based long-term incentives, flexible work models where possible, and time-off plans.