Principal Business Manager, Early Clinical Development (ECD)

About the role

The Early Clinical Development (ECD) Business Manager acts as a key strategic advisor to the assigned Leadership Team and Senior Leaders within gRED ECD, reporting directly to the ECD Chief of Staff. The role leads short- and long-term business planning, strategy formulation, resource allocation, budget oversight and execution across the department. On-site presence at the South San Francisco campus is expected 3 to 4 times per week, depending on business needs.

Key responsibilities

• Build cross-functional collaboration, networks across functions, enterprise teams and external partners, and drive talent development, engagement programs, workshops and recognition initiatives.
• Act as a thought partner to executive leadership, advising on priorities and helping shape enterprise strategy.
• Facilitate leadership meetings with clear agendas, concise documentation and rigorous follow-up on action items.
• Oversee annual planning, resource forecasting, budget allocation and goal setting.
• Recommend operational strategies that balance innovation with guardrails, and resolve complex business challenges by mobilizing stakeholders.

Required profile

• Bachelor's degree required; project management or process improvement certifications (PMP, Six Sigma, Agile, Change Management) preferred.
• 5 to 10 years in business management, cross-functional initiatives or operations programs; clinical development experience preferred.
• Ability to work over 8 hours per day or 40 hours per week, including early morning or late-night calls, and to respond quickly to emails and calls.
• Able to sit or stand for long periods, carry up to 10 lbs of materials and travel between campus buildings, and travel domestically and internationally as needed.
• Relocation benefits are not available for this posting.

Required skills

• Strategic planning, project management and business process improvement.
• Team facilitation and change management and communication.
• Strong written, oral and presentation skills.

What we offer

• Expected salary range of $136,100 - $252,700, depending on experience, qualifications and location; actual pay set by the company.
• Possible discretionary annual bonus based on individual and company performance.
• Benefits described in the original listing.