Postdoctoral Fellow – Single-Cell Genomics & CRISPR Technology

About the role

The Darmanis and Regev labs at Genentech are seeking a Postdoctoral Fellow to focus on technology development at the forefront of functional genomics, building single-cell, CRISPR-based genetic perturbation screens and multi-omic technologies. The fellow works with scientific collaborators across the community to solve fundamental biological questions and publish high-impact science.

Key responsibilities

• Spearhead the design, development and optimisation of novel technologies for single-cell multi-omics, with a primary focus on high-throughput CRISPR genetic perturbation screens.
• Interpret and analyse complex single-cell genomics data using analytical methods and AI-based approaches.
• Collaborate with academic and scientific partners to advance novel technological platforms.
• Publish primary research in high-impact, peer-reviewed journals and present findings at internal seminars and international conferences.

Required profile

• PhD (or near completion) in Molecular Biology, Genetics, Biochemistry, Biomedical Engineering, Bioengineering or a related discipline.
• Strong background in molecular biology, genomics, cell biology or bioengineering, with the ability or enthusiasm to learn and apply single-cell multi-omic assays or CRISPR-based technologies.
• Demonstrated scientific productivity, such as first-author publications, preprints or patent applications.
• Excellent oral and written communication, strong problem-solving and a collaborative attitude.

Required skills

• Proficiency in standard molecular biology techniques and NGS library preparation downstream of single-cell assays, with exposure to short- and long-read sequencing platforms.
• Working knowledge of or proficiency in computational genomics analysis using R and/or Python.

What we offer

• Expected salary of $100,000 to $106,500 for the California location; actual pay depends on experience, qualifications and location.
• Competitive salary and fully funded research expenses.
• Mentorship, access to seminars, professional development workshops and networking opportunities.
• Relocation benefits.