Medical Director: Gastroenterology, Pulmonary, Rheumatology, Nephrology

About the role

The Early Clinical Development (ECD) OMNI group at Genentech drives innovation across a broad portfolio of immunology indications, from First-in-Human studies through Proof-of-Concept and initial pivotal decisions. This Medical Director role covers Gastroenterology, Pulmonary, Rheumatology and Nephrology, with relocation benefits available and an expectation of onsite presence at the South San Francisco campus at least 3 days a week.

Key responsibilities

• Drive clinical trial design: author clinical protocols and design early-phase (Phase I/II) studies to establish biologic and clinical proof-of-concept for novel molecular entities.
• Serve as Medical Monitor: provide medical oversight, safety monitoring and clinical expertise across active trials, working with trial sites, investigators and CROs.
• Lead cross-functional strategy: represent Clinical Science on multi-disciplinary Clinical Science Teams and Protocol Execution Teams, integrating biomarkers, safety, regulatory and commercial insights.
• Guide regulatory and asset strategy: author clinical sections for INDs, IBs and health authority briefing materials, supporting interactions with the FDA and EMA.
• Engage global scientific leaders: collaborate with internal research groups, external Key Opinion Leaders and scientific advisory boards to refine disease area strategies and inform portfolio decisions.

Required profile

• M.D. with board certification or eligibility in Gastroenterology, Pulmonary, Rheumatology, Nephrology or a related specialty (M.D./Ph.D. preferred).
• 0-2 years of experience for Medical Director, 2+ years for Lead Medical Director, in clinical, translational or basic research within academia or the biopharmaceutical industry, with a focus on immunology or inflammation.
• Thorough understanding of early clinical drug development (Phases I-II), trial methodology, GCP/ICH guidelines and clinical data interpretation.
• Able to synthesize biomarker and safety data to shape asset strategy and communicate effectively with investigators, regulators and partners.

What we offer

• Salary range of $213,400-$396,200 (Medical Director) and $233,500-$433,600 (Lead Medical Director), depending on experience and qualifications.
• Discretionary annual bonus based on individual and company performance.
• Relocation benefits.