Global Pharmacovigilance Senior Medical Director

About the role

Beeline Medicines is seeking a Global Pharmacovigilance Senior Medical Director to lead drug safety across its immunology and inflammation pipeline, including the lead lupus program. This senior physician-level position provides medical and scientific leadership for benefit‑risk evaluation, signal assessment and safety governance worldwide.

Key responsibilities

• Serve as the senior physician for safety science and pharmacovigilance, setting medical standards for individual case safety reports, aggregate analyses, signal evaluations and benefit‑risk assessments across the I&I portfolio.
• Define strategy and quality standards for medical review and clinical interpretation of safety data from clinical trials, spontaneous reports, literature and real‑world sources.
• Provide medical oversight of the pharmacovigilance vendor’s safety evaluation output to ensure timely, accurate and scientifically rigorous assessments.
• Act as the primary physician representative to Health Authorities, Data Safety Monitoring Boards and external advisory bodies for assigned programs.
• Partner with Clinical Development, Regulatory Affairs, Medical Affairs and Program Leadership to deliver medically sound, strategically aligned safety leadership.

Required profile

• Physician (MD) or equivalent with extensive experience in pharmacovigilance and drug safety.
• Proven senior‑level leadership in benefit‑risk evaluation, signal assessment and safety governance for immunology/inflammation programs.
• Experience interacting with regulatory authorities, DSMBs and external advisory committees.
• Ability to influence cross‑functional teams and drive scientific insight.

Required skills

• Pharmacovigilance
• Benefit‑risk evaluation
• Signal assessment
• Medical review of safety data
• Clinical data interpretation