Director of Pharmacokinetics

About the role

The Pharmacokinetics, Dynamics, Metabolism and Bioanalytics (PDMB) function is seeking a dynamic leader to head the Drug Metabolism and Pharmacokinetics (DMPK) group in West Point, Pennsylvania. You will guide a team of experienced scientists and bench researchers, driving innovative ADME studies that support discovery programs across multiple modalities.

Key responsibilities

• Provide strategic scientific and operational leadership for DMPK scientists, ensuring high‑quality data delivery and cross‑functional collaboration.
• Mentor and develop staff, fostering career growth and talent retention.
• Drive the design, execution, and interpretation of in silico, in vitro, and in vivo studies to inform lead selection and first‑in‑human decisions.
• Integrate preclinical ADME, PK, and pharmacology data for translational PK/PD modeling and dose justification.

Required profile

• PhD in Chemistry, Pharmaceutical Sciences, Pharmacology, Biomedical Engineering, Biochemistry or related field with at least 8 years of drug discovery experience.
• Minimum 3 years of management or supervisory experience leading scientific teams.
• Proven ability to communicate complex scientific data to interdisciplinary teams and senior management.

Required skills

• Deep expertise in ADME, drug metabolism, and pharmacokinetics.
• Experience with PK/PD and PBPK modeling.
• Proficiency in in silico approaches, modern DMPK instrumentation, and bioanalytical assays.
• Strong leadership, problem‑solving, and collaboration abilities.

What we offer

• Competitive salary range $173,200 – $272,600 per year, with annual bonus and long‑term incentives.
• Comprehensive benefits package including medical, dental, vision, 401(k), paid holidays, vacation, and sick days.
• Opportunity to influence a large, innovative pipeline and develop the next generation of leaders.