Associate Director/Director, Data Management

About the role

Climb Bio is building its Phase 1‑through‑3 data management capability from the ground up. Reporting to the Vice President, Head of Biometrics, the Associate Director/Director will own database design, vendor management and delivery of clean, submission‑ready data.

Key responsibilities

• Design and build clinical database architecture, establishing edit checks, structures and specifications that meet analysis and regulatory requirements.
• Own end‑to‑end user acceptance testing (UAT) for database builds, from test plan development to final sign‑off.
• Manage data management timelines and deliverables across studies, holding CROs and vendors accountable from first patient in through database lock.
• Direct selection and performance oversight of data management CROs and vendors, serving as primary escalation point for data quality and timeline issues.
• Partner with Biostatistics, Clinical Operations and Regulatory to align data management plans, CRF design and database specifications with study protocols.
• Establish data management standards, SOPs and quality control processes that scale with the growing portfolio.
• Lead data cleaning, query resolution and reconciliation to ensure inspection‑ready, submission‑quality data at lock.
• Represent Data Management in cross‑functional program governance, reporting on timelines, risks and trade‑offs.

Required profile

• Bachelor's degree in life sciences or related field.
• 10+ years of clinical data management experience (12+ years for Director level), including taking a database through Phase 3 lock.
• Demonstrated experience designing clinical databases and leading UAT execution.
• Experience managing CRO and data management vendor relationships.
• Working knowledge of GCP and applicable regulatory requirements.

Required skills

• Clinical database architecture design.
• User acceptance testing (UAT) execution.
• CRO and vendor performance oversight.
• Knowledge of GCP and regulatory data management standards.
• Proficiency with industry‑standard clinical database and EDC platforms.

What we offer

• Hybrid work arrangement based in Wellesley, MA.
• Base salary commensurate with experience.
• Discretionary annual bonus.
• Comprehensive medical, dental and vision benefits.
• Life & disability insurance, 401k match.
• Generous paid time off and equity participation.